Microwave-assisted alcoholysis of dialkyl phosphites by ethylene glycol and ethanolamine

Keglevich, György and Bálint, Erika and Tajti, Ádám and Mátravölgyi, Béla and Balogh, György Tibor and Balint, Mária and Ilia, Gheorghe (2014) Microwave-assisted alcoholysis of dialkyl phosphites by ethylene glycol and ethanolamine. PURE AND APPLIED CHEMISTRY, 86 (11). pp. 1723-1728. ISSN 0033-4545

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Abstract

A study on the microwave-assisted alcoholysis of diethyl phosphite with ethylene glycol revealed that after optimization of the conditions (molar ratio, temperature and time), the target "monomer," (HOCH2CH2O)(2)P(O)H was formed in a proportion of 59 %, but with an incomplete conversion. The formation of the (HOCH2CH2O)(EtO)P(O)H and H(EtO)(O)POCH2CH2OP(O)(OEt)H by-products was, in most cases, inevitable. The alcoholysis with ethanolamine was more efficient and took place in a conversion of 100 % to afford H2NCH2CH2O)(2)P(O)H in a proportion of 85 %. An alkyl substituent on the N-atom prevented the alcoholysis.

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