Nazirizadeh, Yousef and Behrends, Volker and Prósz, Aurél and Orgován, Norbert and Horváth, Róbert (2016) Intensity interrogation near cutoff resonance for label-free cellular profiling. SCIENTIFIC REPORTS, 6. p. 24685. ISSN 2045-2322
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Abstract
We report a method enabling intensity-based readout for label-free cellular assays, and realize a reader device with the same footprint as a microtiter plate. For unambiguous resonance intensity measurements in resonance waveguide grating (RWG) sensors, we propose to apply resonances near the substrate cutoff wavelength. This method was validated in bulk refractive index, surface bilayer and G protein-coupled receptor (GPCR) experiments. The significantly reduced size of the reader device opens new opportunities for easy integration into incubators or liquid handling systems.
| Item Type: | Article |
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| Subjects: | Q Science / természettudomány > QD Chemistry / kémia |
| SWORD Depositor: | MTMT SWORD |
| Depositing User: | MTMT SWORD |
| Date Deposited: | 27 May 2016 10:48 |
| Last Modified: | 27 May 2016 10:48 |
| URI: | http://real.mtak.hu/id/eprint/35426 |
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