Secondary tumoural valvulopathy in a dog

Jakab, Csaba and Szász, Attila and Kulka, Janina and Baska, Ferenc and Rusvai, Miklós and Gálfi, Péter and Németh, Tibor (2009) Secondary tumoural valvulopathy in a dog. Acta Veterinaria Hungarica, 57 (1). pp. 63-67. ISSN 0236-6290

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Abstract

This short report describes a case of tricuspid valvular metastasis of canine disseminated histiocytic sarcoma in a 9-year-old female Rottweiler. Immunohistochemically the malignant neoplastic cells gave a strong reaction for vimentin and lysozyme, and showed negativity for serotonin, CD3, CD79a and cytokeratin. The intratumoural microvessels were detected by immunohistochemistry using CD31 and claudin-5. This appears to be the first report of a valvular metastasis of canine malignant histiocytosis.

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