Shared G12 VP7 gene among human and bovine rotaviruses detected in cameroonian villages

Ndze, Valentine and Achidi, Eric and Papp, Hajnalka and Kovács, Eszter and Farkas, Szilvia and Adiogo, Dieudonne and Kisfali, Péter and Ngeng, Marxcel and Abena, Marie and Martella, Vito and Esona, Mathew and Bányai, Krisztián (2013) Shared G12 VP7 gene among human and bovine rotaviruses detected in cameroonian villages. Acta Microbiologica et Immunologica Hungarica, 60 (1). pp. 21-28. ISSN 1217-8950

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Abstract

Group A rotaviruses (RVA) are an important enteric pathogen in humans and livestock animals. Transmission of animal RVA strains to humans has been documented on several occasions. A reverse route of transmission of RVA under natural circumstances is anticipated, although evidence is scarce. However, experimental studies indicated that animals can be infected with human RVAs. By screening the stool samples collected from 157 cattle during 2011 in two Cameroonian villages, four samples (2.5%) were found positive for RVA. Upon sequence analysis of a 410 bp fragment of the VP7 gene, the RVA strains shared up to 100% nt identity to each other and to G12 RVAs identified in human patients living in the same geographic regions. This finding provides evidence for a human-to-animal transmission of an epidemic human rotavirus strain.

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