REAL

Computer aided design of triplet forming artificial nucleobases

Fenyo, R. and Timár, Zoltán and Pálinkó, István and Penke, Botond (1999) Computer aided design of triplet forming artificial nucleobases. NUCLEOSIDES AND NUCLEOTIDES, 18 (4-5). pp. 1127-1129. ISSN 0732-8311

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Abstract

Triplex forming oligonucleotides could prevent genetic transcription at the level of genes. Nucleotide bases with the capability of specific H-bonding interactions with base pairs in the major groove of DNA have been designed. Calculations by semiempirical methods lead to four compounds as possible triplet forming nucleobases.

Item Type: Article
Additional Information: XIII International Round Table Conference on Nucleosides, Nucleotides and their Biological Applications Location: MONTPELLIER, FRANCE Date: SEP 06-10, 1998.
Subjects: Q Science / természettudomány > QH Natural history / természetrajz > QH301 Biology / biológia > QH3011 Biochemistry / biokémia
Q Science / természettudomány > QH Natural history / természetrajz > QH301 Biology / biológia > QH3015 Molecular biology / molekuláris biológia
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 30 May 2013 07:45
Last Modified: 30 May 2013 07:45
URI: http://real.mtak.hu/id/eprint/5363

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