Items where Author is "Mernyák, Erzsébet"

Senobar Tahaei, Seyyed Ashkan and Kulmány, Ágnes and Minorics, Renáta and Kiss, Anita and Szabó, Zoltán and Germán, Péter and Szebeni, Gábor J. and Gémes, Nikolett and Mernyák, Erzsébet and Zupkó, István (2023) Antiproliferative and Antimetastatic Properties of 16-Azidomethyl Substituted 3-O-Benzyl Estrone Analogs. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (18). No-13749. ISSN 1422-0067

Ali, Hazhmat and Traj, Péter and Szebeni, Gábor J. and Gémes, Nikolett and Resch, Vivien and Paragi, Gábor and Mernyák, Erzsébet and Minorics, Renáta and Zupkó, István (2023) Investigation of the Antineoplastic Effects of 2-(4-Chlorophenyl)-13α-Estrone Sulfamate against the HPV16-Positive Human Invasive Cervical Carcinoma Cell Line SiHa. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (7). No-6625. ISSN 1422-0067

Senobar Tahaei, Seyyed Ashkan and Kulmány, Ágnes and Minorics, Renáta and Kiss, Anita and Szabó, Zoltán and Szebeni, Gábor and Gémes, Nikolett and Mernyák, Erzsébet (2023) Antiproliferative and Antimetastatic Properties of 16-Azidomethyl Substituted 3-O-Benzyl Estrone Analogs. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (18). ISSN 1661-6596

Mernyák, Erzsébet and Bartha, Sándor and Kóczán, Lili and Jójárt, Rebeka and Resch, Vivien and Paragi, Gábor and Vágvölgyi, Máté and Hunyadi, Attila and Bruszel, Bella and Zupkó, István and Minorics, Renáta (2021) Microwave-assisted Phospha-Michael addition reactions in the 13α-oestrone series and in vitro antiproliferative properties. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 36 (1). pp. 1931-1937. ISSN 1475-6366

Sinreih, Masa and Jójárt, Rebeka and Kele, Zoltán and Budefeld, Tomaz and Paragi, Gábor and Mernyák, Erzsébet and Lanisnik-Rizner, Tea (2021) Synthesis and evaluation of AKR1C inhibitory properties of A-ring halogenated oestrone derivatives. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 36 (1). pp. 1500-1508. ISSN 1475-6366

Laczkó-Rigó, Réka and Bakos, Éva and Jójárt, Rebeka and Tömböly, Csaba and Mernyák, Erzsébet and Özvegy-Laczka, Csilla (2021) Selective antiproliferative effect of C-2 halogenated 13α-estrones on cells expressing Organic anion-transporting polypeptide 2B1 (OATP2B1). TOXICOLOGY AND APPLIED PHARMACOLOGY. ISSN 0041-008X

Tuerkova, Alzbeta and Ungvári, Orsolya and Laczkó-Rigó, Réka and Mernyák, Erzsébet and Szakács, Gergely and Özvegy-Laczka, Csilla and Zdrazil, Barbara (2021) Data-Driven Ensemble Docking to Map Molecular Interactions of Steroid Analogs with Hepatic Organic Anion Transporting Polypeptides. JOURNAL OF CHEMICAL INFORMATION AND MODELING. ISSN 1549-9596

Kiss, Anita and Jójárt, Rebeka and Mernyák, Erzsébet and Bartha, Sándor and Minorics, Renáta and Zupkó, István and Schneider, Gyula (2021) Novel preparation of substituted oxazolines condensed to d-ring of estrane skeleton and characterization of their antiproliferative properties. STEROIDS. ISSN 0039-128X (In Press)

Jójárt, Rebeka and Laczkó-Rigó, Réka and Klement, Máté and Kőhl, Gabriella and Kecskeméti, Gábor and Laczka, Csilla and Mernyák, Erzsébet (2021) Design, synthesis and biological evaluation of novel estrone phosphonates as high affinity organic anion-transporting polypeptide 2B1 (OATP2B1) inhibitors. BIOORGANIC CHEMISTRY. ISSN 0045-2068 (Unpublished)

Sinreih, Maša and Jójárt, Rebeka and Kele, Zoltán and Büdefeld, Tomaž and Paragi, Gábor and Mernyák, Erzsébet (2021) Synthesis and evaluation of AKR1C inhibitory properties of A-ring halogenated oestrone derivatives. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 36 (1). pp. 1500-1508. ISSN 1475-6366

Jójárt, Rebeka and Senobar Tahaei, Seyyed Ashkan and Trungel-Nagy, Péter and Kele, Zoltán and Minorics, Renáta and Paragi, Gábor and Zupkó, István and Mernyák, Erzsébet (2021) Synthesis and evaluation of anticancer activities of 2- or 4-substituted 3-(N-benzyltriazolylmethyl)-13α-oestrone derivatives. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 36 (1). pp. 58-67. ISSN 1475-6366

Traj, Péter and Abdolkhaliq, Ali Hazhmat and Németh, Anett and Dajcs, Sámuel Trisztán and Tömösi, Ferenc and Zupkó, István and Mernyák, Erzsébet (2021) Transition metal-catalyzed A-ring C–H activations and C(sp2)–C(sp2) couplings in the 13α-oestrone series and in vitro evaluation of antiproliferative properties. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 36 (1). pp. 895-902. ISSN 1475-6366 (print); 1475-6374 (online)

Jójárt, Rebeka and Ali, Hazhmat and Horváth, Gergely and Kele, Zoltán and Zupkó, István and Mernyák, Erzsébet (2020) Pd-Catalyzed Suzuki–Miyaura couplings and evaluation of 13α-estrone derivatives as potential anticancer agents. STEROIDS, 164. ISSN 0039-128X

Laczkó-Rigó, Réka and Jójárt, Rebeka and Mernyák, Erzsébet and Bakos, Éva and Tuerkova, Alzbeta and Özvegy-Laczka, Csilla (2020) Structural dissection of 13-epiestrones based on the interaction with human Organic anion-transporting polypeptide, OATP2B1. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 200. pp. 1-10. ISSN 0960-0760

Herman, Bianka Edina and Kiss, Anita and Wölfling, János and Mernyák, Erzsébet and Szécsi, Mihály and Schneider, Gyula (2019) Synthesis of substituted 15β-alkoxy estrone derivatives and their cofactor-dependent inhibitory effect on 17β-HSD1. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 34 (1). pp. 1271-1286. ISSN 1475-6366

Jójárt, Rebeka and Traj, Péter and Kovács, Édua and Horváth, Ágnes and Schneider, Gyula and Szécsi, Mihály and Pál, Attila and Paragi, Gábor and Mernyák, Erzsébet (2019) Synthesis, Biological Evaluation and Docking Studies of 13-Epimeric 10-fluoro- and 10-Chloroestra-1,4-dien-3-ones as Potential Aromatase Inhibitors. MOLECULES, 24 (9). No.-1783. ISSN 1420-3049

Bacsa, Ildikó and Szemerédi, Dávid and Wölfling, János and Schneider, Gyula and Fekete, Lilla and Mernyák, Erzsébet (2018) The first Pd-catalyzed Buchwald–Hartwig aminations at C-2 or C-4 in the estrone series. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY. ISSN 1860-5397

Gyovai, András and Minorics, Renáta and Kiss, Anita and Mernyák, Erzsébet and Schneider, Gyula and Szekeres, András and Kerekes, Erika and Ocsovszki, Imre and Zupkó, István (2018) Antiproliferative Properties of Newly Synthesized 19-Nortestosterone Analogs Without Substantial Androgenic Activity. FRONTIERS IN PHARMACOLOGY, 9. pp. 1-11. ISSN 1663-9812

Jójárt, Rebeka and Pécsy, Balázs and Keglevich, György and Szécsi, Mihály and Rigó, Réka and Laczka, Csilla and Mernyák, Erzsébet (2018) Pd-Catalyzed microwave-assisted synthesis of phosphonated 13α-estrones as potential OATP2B1, 17β-HSD1 and/or STS inhibitors. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 14. pp. 2838-2845. ISSN 1860-5397

Bacsa, Ildikó and Herman, Bianka Edina and Jójárt, Rebeka and Herman, Kevin Stefán and Wölfling, János and Schneider, Gyula and Varga, Mónika and Tömböly, Csaba and Szécsi, Mihály and Mernyák, Erzsébet (2018) Synthesis and structure–activity relationships of 2- and/or 4-halogenated 13β- and 13α-estrone derivatives as enzyme inhibitors of estrogen biosynthesis. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 33 (1). pp. 1271-1282. ISSN 1475-6366 (print); 1475-6374 (online)

Fröhlich, Tony and Kiss, Anita and Wölfling, János and Mernyák, Erzsébet and Kulmány, Ágnes E. and Minorics, Renáta and Zupkó, István and Schneider, Gyula (2018) Synthesis of Artemisinin-Estrogen Hybrids Highly Active against HCMV, P. falciparum, and Cervical and Breast Cancer. ACS MEDICINAL CHEMISTRY LETTERS, 9 (11). pp. 1-6. ISSN 1948-5875

Bacsa, Ildikó and Konc, Csilla and Orosz, Anna Boglárka and Kecskeméti, Gábor and Rigó, Réka and Laczka, Csilla and Mernyák, Erzsébet (2018) Synthesis of novel C-2- or C-15-labeled BODIPY—estrone conjugates. MOLECULES, 23 (4). p. 821. ISSN 1420-3049

Bózsity, Noémi and Minorics, Renáta and Szabó, Johanna and Mernyák, Erzsébet and Schneider, Gyula and Wölfling, János and Ocsovszki, Imre and Zupkó, István (2017) Mechanism of antiproliferative action of a new D-secoestrone-triazole derivative in cervical cancer cells and its effect on cancer cell motility. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 165. pp. 247-257. ISSN 0960-0760

Bacsa, Ildikó and Jójárt, Rebeka and Wölfling, János and Schneider, Gyula and Herman, Bianka Edina and Szécsi, Mihály and Mernyák, Erzsébet (2017) Synthesis of novel 13 α-estrone derivatives by Sonogashira coupling as potential 17 β-HSD1 inhibitors. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 13. pp. 1303-1309. ISSN 1860-5397

Bózsity, Noémi and Minorics, Renáta and Szabó, Johanna and Mernyák, Erzsébet and Schneider, Gyula and Wölfling, János and Wang, Hui-Chun and Wu, Chin-Chung and Ocsovszki, Imre and Zupkó, István (2016) Mechanism of antiproliferative action of a new D-secoestrone-triazole derivative in cervical cancer cells and its effect on cancer cell motility. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. ISSN 0960-0760 (In Press)

Schneider, Gyula and Kiss, Anita and Mernyák, Erzsébet and Benke, Zsanett and Wölfling, János and Frank, Éva and Bózsity, Noémi and Gyovai, András and Minorics, Renáta and Zupkó, István (2016) Stereocontrolled synthesis of the four 16-hydroxymethyl-19- nortestosterone isomers and their antiproliferative activities. STEROIDS, 105. pp. 113-120. ISSN 0039-128X

Schneider, Gyula and Kiss, Anita and Mernyák, Erzsébet and Benke, Zsanett and Wölfling, János and Frank, Éva and Bózsity, Noémi and Gyovai, András and Minorics, Renáta and Zupkó, István (2016) Stereocontrolled synthesis of the four 16-hydroxymethyl-19-nortestosterone isomers and their antiproliferative activities. STEROIDS, 105. pp. 113-120. ISSN 0039-128X

Szabó, Johanna and Pataki, Zoltán and Wölfling, János and Schneider, Gyula and Bózsity, Noémi and Minorics, Renáta and Zupkó, István and Mernyák, Erzsébet (2016) Synthesis and biological evaluation of 13a-estrone derivatives as potential antiproliferative agents. STEROIDS, 113. pp. 14-21. ISSN 0039-128X

Szabó, Johanna and Pataki, Zoltán and Wölfling, János and Schneider, Gyula and Bózsity, Noémi and Minorics, Renáta and Zupkó, István and Mernyák, Erzsébet (2016) Synthesis and biological evaluation of 13α-estrone derivatives as potential antiproliferative agents. STEROIDS, 113. pp. 14-21. ISSN 0039-128X

Szabó, Johanna and Jerkovics, Nóra and Schneider, Gyula and Wölfling, János and Bózsity, Noémi and Minorics, Renáta and Zupkó, István and Mernyák, Erzsébet (2016) Synthesis and in Vitro Antiproliferative Evaluation of C-13 Epimers of Triazolyl-D-Secoestrone Alcohols: The First Potent 13α-D-Secoestrone Derivative. MOLECULES, 21 (611). ISSN 1420-3049

Szabó, Johanna and Jerkovics, Nóra and Schneider, Gyula and Wölfling, János and Bózsity, Noémi and Minorics, Renáta and Zupkó, István and Mernyák, Erzsébet (2016) Synthesis and in Vitro Antiproliferative Evaluation of C-13 Epimers of Triazolyl-D-Secoestrone Alcohols: The First Potent 13α-D-Secoestrone Derivative. MOLECULES, 21 (5). pp. 1-13. ISSN 1420-3049

Szabó, Nikoletta and Iványi, Zoltán and Szécsi, Mihály and Julesz, János and Mernyák, Erzsébet and Huber, Judit and Wölfling, János and Minorics, Renáta and Zupkó, István and Schneider, Gyula (2015) Synthesis of methoxycarbonylpyrazolylandrostene derivatives, and their potential inhibitory effect on androgen biosynthesis and cell proliferation. STEROIDS, 98. pp. 143-152. ISSN 0039-128X

Schneider, Gyula and Görbe, Tamás and Mernyák, Erzsébet and Wölfling, János and Holczbauer, Tamás and Minorics, Renáta and Zupkó, István (2015) Synthesis of novel 17-(5’-iodo)triazolyl-3-methoxyestrane epimers via Cu(I)-catalyzed azide-alkyne cycloadditon, and an evaluation of their cytotoxic activity in vitro. STEROIDS, 98. pp. 153-165. ISSN 0039-128X

Mernyák, Erzsébet and Kovács, Ida and Minorics, Renáta and Sere, Péter and Czégány, Dóra and Wölfling, János and Schneider, Gyula and Újfaludi, Zsuzsanna and Boros, Imre Miklós and Zupkó, István (2015) Synthesis of trans-16-triazolyl-13α-methyl-17-estradiol diastereomers and the effects of structural modifications on their in vitro antiproliferative activities. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 150. pp. 123-134. ISSN 0960-0760

Minorics, Renáta and Bózsity, Noémi and Molnár, Judit and Wölfling, János and Mernyák, Erzsébet and Zupkó, István (2015) A molecular understanding of d-homoestrone-induced G2/M cell cycle arrest in HeLa human cervical carcinoma cells. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, in pre. 10.1111/jcmm.12587. ISSN 1582-1838

Mernyák, Erzsébet (2009) 1,3 - Dipólusok képzése és azok cikloaddíciós reakciói a 13 alfa-ösztron sorban = Synthesis of 1,3 - dipoles and their cycloaddition reactions in the 13a-estrone series. Project Report. OTKA.

Wölfling, János and Julesz, János and Mernyák, Erzsébet and Nagyné dr. Frank, Éva and Schneider, Gyula and Szájli, Ágota and Szécsi, Mihály and Tóth, István (2009) Antiandrogén kardenolid analógok szintézise és biológiai hatásvizsgálata = Synthesis and biological effect investigations of antiandrogen cardenolide analogues. Project Report. OTKA.

Schneider, Gyula and Magyar, Angéla Andrea and Mernyák, Erzsébet and Nagyné dr. Frank, Éva and Wölfling, János (2007) Szteránvázas vegyületek szintézise = Synthesis of Steroid Compounds. Project Report. OTKA.