Manczinger, Máté and Boross, Gábor and Kemény, Lajos and Müller, Viktor and Lenz, Tobias L. and Papp, Balázs and Pál, Csaba (2019) Pathogen diversity drives the evolution of generalist MHC-II alleles in human populations. PLOS BIOLOGY, 17 (1). ISSN 1544-9173
|
Text
journal.pdf Available under License Creative Commons Attribution. Download (1MB) | Preview |
Official URL: http://doi.org/10.1371/journal.pbio.3000131
Abstract
Whereas specialist major histocompatibility complex (MHC) molecules initiate immune response against only relatively few pathogens, generalists provide protection against a broad range. Accordingly, this study shows that the geographical distribution of generalist MHC alleles in human populations reflects exposure to diverse infectious diseases.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science / természettudomány > QH Natural history / természetrajz > QH301 Biology / biológia |
| SWORD Depositor: | MTMT SWORD |
| Depositing User: | MTMT SWORD |
| Date Deposited: | 23 Nov 2019 03:17 |
| Last Modified: | 20 Apr 2023 11:57 |
| URI: | http://real.mtak.hu/id/eprint/103639 |
Actions (login required)
 |
Edit Item |
