Rapp, Judit and Járomi, Luca and Kvell, Krisztian and Miskei, Gyorgy and Pongracz, Judit (2017) WNT signaling - lung cancer is no exception. RESPIRATORY RESEARCH, 18 (1). p. 167. ISSN 1465-9921 (print); 1465-993X (online)
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Abstract
Since the initial discovery of the oncogenic activity of WNT ligands our understanding of the complex roles for WNT signaling pathways in lung cancers has increased substantially. In the current review, the various effects of activation and inhibition of the WNT signaling pathways are summarized in the context of lung carcinogenesis. Recent evidence regarding WNT ligand transport mechanisms, the role of WNT signaling in lung cancer angiogenesis and drug transporter regulation and the importance of microRNA and posttranscriptional regulation of WNT signaling are also reviewed.
Item Type: | Article |
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Subjects: | Q Science / természettudomány > QR Microbiology / mikrobiológia > QR180 Immunology / immunológia |
Depositing User: | dr Krisztian Kvell |
Date Deposited: | 31 May 2023 06:09 |
Last Modified: | 31 May 2023 06:09 |
URI: | http://real.mtak.hu/id/eprint/166353 |
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