The release of encapsulated phenolics following different in vitro digestion methods

Korkmaz, N. and El, S.N. (2025) The release of encapsulated phenolics following different in vitro digestion methods. ACTA ALIMENTARIA: AN INTERNATIONAL JOURNAL OF FOOD SCIENCE, 54 (2). pp. 197-204. ISSN 0139-3006

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Abstract

In this study, polyphenol-rich extracts obtained from apple peel waste, red pepper, and grape seed were encapsulated to solve the problems originating from chemical or physical stability and to determine the bioaccessibility of phenolics. The bioaccessibility of encapsulated phenolic extracts during simulated digestion in the gastrointestinal tract was investigated using two different static in vitro models. The obtained phenolic-loaded chitosan particles had encapsulation efficiency (EE) and loading capacity (LC) in the range of 81.72–89.93% and 42.38–69.28% in all samples, respectively. The bioaccessibilities of phenolics determined following in vitro digestion methods in all samples were significantly different ( P < 0.05). Polyphenol-chitosan loaded particles showed higher bioaccessibilities in all samples.

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