Economic analysis of a bioprocess (successive tryptic and microbial hydrolysis of milk proteins) for the producing of dairy protein formula having lower allergenic activity

Csighy, Attila and Abdisa, Kenbon Beyene and Bánvölgyi, Szilvia and Lakner, Zoltán and Némethné Szerdahelyi, Emőke and Friedrich, László Ferenc and Molnár, Máté András and Nath, Arijit and Koris, András (2025) Economic analysis of a bioprocess (successive tryptic and microbial hydrolysis of milk proteins) for the producing of dairy protein formula having lower allergenic activity. PROGRESS IN AGRICULTURAL ENGINEERING SCIENCES, 21 (1). pp. 393-423. ISSN 1786-335X

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Abstract

Allergenic activity of milk proteins, mainly casein, α-lactalbumin and β-globulin is one of the limiting factors for the dietary intake of dairy foods. Lab-scale experimental results about the development of dairy protein formula with lower allergenic activity by tryptic and microbial hydrolysis of dairy proteins in a successive way were published previously; however, the economic analysis of this bioprocess was not explored. The aim of the present investigation is to perform economic analysis of the proposed process scheme. The mentioned process schemes were developed by the SuperPro Designer software (v. 12, Intelligen, Inc., USA) and concepts from chemical engineering. According to estimated profitability indicators (gross profit, net profit, gross margin, net present value, payback time, return on investment and internal rate of return), it may be considered that successive tryptic and microbial hydrolysis of milk proteins could be a suitable process scheme to produce protein formula with lower allergenic activity in dairy industry.

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