Effect of Nenas honey supplementation on the oxidative status of undergraduate students

Goon, J. and Choor, C. and Ainaa, R. and Sze, X. and Syahriah, M. and Syamimi, M. and Rashidi, S. and Mardiyanna, M. and Zakiah, J. (2014) Effect of Nenas honey supplementation on the oxidative status of undergraduate students. Acta Alimentaria, 43 (1). pp. 182-190. ISSN 0139-3006

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Abstract

Honey is a dietary antioxidant as it contains phenolic compounds, such as flavonoids and phenolic acids. Antioxidants are non-nutritive, biologically active ingredients in food that reduce oxidative stress. The antioxidant content in each type of honey varies depending on its source. This study was aimed to determine the effect of Nenas honey supplementation on the oxidative status of a group of healthy medical students. They were divided into two groups; control (n=10) and supplemented (n=13), where 1 tablespoon of Nenas honey was given each day. Blood sampling was done at baseline, 1^st and 2^nd month of the study for determination of DNA damage and antioxidant enzyme activities, such as superoxide dismutase (SOD), glutathione peroxidise (GPx), and catalase (CAT). Results showed that Nenas honey increased the level of DNA damage at the 1^st month but reduced it significantly at the 2^nd month as compared to control. GPx and CAT activities also decreased significantly with honey supplementation throughout the study, though no changes were observed in SOD activity. Fasting glucose levels remained within the normal range with honey supplementation. In conclusion, Nenas honey decreases oxidative stress which leads to a reduction of antioxidant enzyme activities in the body.

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