Fenyo, R. and Timár, Zoltán and Pálinkó, István and Penke, Botond (1999) Computer aided design of triplet forming artificial nucleobases. NUCLEOSIDES AND NUCLEOTIDES, 18 (4-5). pp. 1127-1129. ISSN 0732-8311
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Abstract
Triplex forming oligonucleotides could prevent genetic transcription at the level of genes. Nucleotide bases with the capability of specific H-bonding interactions with base pairs in the major groove of DNA have been designed. Calculations by semiempirical methods lead to four compounds as possible triplet forming nucleobases.
| Item Type: | Article |
|---|---|
| Additional Information: | XIII International Round Table Conference on Nucleosides, Nucleotides and their Biological Applications Location: MONTPELLIER, FRANCE Date: SEP 06-10, 1998. |
| Subjects: | Q Science / természettudomány > QH Natural history / természetrajz > QH301 Biology / biológia > QH3011 Biochemistry / biokémia Q Science / természettudomány > QH Natural history / természetrajz > QH301 Biology / biológia > QH3015 Molecular biology / molekuláris biológia |
| SWORD Depositor: | MTMT SWORD |
| Depositing User: | MTMT SWORD |
| Date Deposited: | 30 May 2013 07:45 |
| Last Modified: | 30 May 2013 07:45 |
| URI: | http://real.mtak.hu/id/eprint/5363 |
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