Monoamines in the central nervous system of Lymnaea stagnalis (Gastropoda) and the effect of pharmacons on the monoamine level

Nemcsók, János and Markova, L. N. and Hiripi, László (1975) Monoamines in the central nervous system of Lymnaea stagnalis (Gastropoda) and the effect of pharmacons on the monoamine level. A Magyar Tudományos Akadémia Tihanyi Biológiai Kutatóintézetének évkönyve, 42. pp. 81-87. ISSN 0365-3005

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Abstract

1. The excitation and emission spectra recorded from the tissue sample correspond to the excitation and emission spectra of DA and NA. 2. Besides serotonin the central nervous system of Lymnaea stagnalis contains dopamine (12.98 µg/g) and noradrenaline (0.63 µg/g) to a high degree DA and NA present in a significant concentration besides serotonin may suggest that DA and NA also play a significant role in th neurotransmission in Lymnaea stagnalis, too. 3. Reserpin and pCPA decreased the serotonin level to a high degree. Nialamid, iproniazid and tranylcypromine known as MAO inhibitors contrary to the expectation, did not increase but rather decreased serotonin level. 4. The reserpin treatment decreased considerably also the level of DA and NA, while tranylcypromine decreased only the NA level noticeably, and hardly altered the level of dopamine.

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