Protecting and reactivating effect of serotonin on the heat-inactivated heart of the fresh-water mussel

Szaharov, Dimitrij A. and Pécsi, Tibor (1965) Protecting and reactivating effect of serotonin on the heat-inactivated heart of the fresh-water mussel. A Magyar Tudományos Akadémia Tihanyi Biológiai Kutatóintézetének évkönyve, 32. pp. 117-121. ISSN 0365-3005

Preview

Text 131_cut_MTA_TihanyiBiologiaiKutIntEvkonyve_32.pdf Download (2MB) | Preview

Abstract

Serotonin within certain limits restores the pulsation of the isolated mussel’s heart that came to a standstill upon the action of high temperature. Heat treatment resulting in the standstill of the heart becomes ineffective if the heart is kept previously in serotonin solution. These facts seem to point out that endogenous serotonin which acts here as a local hormone may have an important part in the automatism of the mussel’s heart. Tryptamine and 5-methoxvtryptamine have a similar protective effect from the heat inactivation of the heart which is, however, about 10 times less active than that of serotonin. On the other hand no such effect was observed, even in the case of high concentrations, when noradrenaline, tyramine, histamine, tryptophan, 5-hydroxytryptophan, 5-hydroxy-N’-dimethyltryptamine and 5-methoxy-N’-acetyltryptamine were applied.

Actions (login required)

Edit Item