Investigation of the effect of 3-4 benzpyrene on amphibia

Matoltsy, Gedeon (1947) Investigation of the effect of 3-4 benzpyrene on amphibia. A Magyar Tudományos Akadémia Tihanyi Biológiai Kutatóintézetének évkönyve, 17. pp. 179-185. ISSN 0365-3005

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Abstract

3-4 benzpyrene does not induce tumours in Triton cristatus and Rana esculenta, but it produces a toxic effect in their bodies. It produces a toxic haemorrhage in the kidneys and liver, parenchym degeneration, fatty-degeneration and necrosis. In frogs it produces edema in the lungs, exudative cells and an edemic swelling of the alveolar wall Edema forms under the skin and in the abdomen. Benzpyrene is excreted by the liver and kidneys.

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