REAL

Studies on the Synthesis of Some Functionalized Azaheterocycles through Oxidative Ring Opening/Ring Closing by Reductive Amination

Nonn, Melinda and Berkecz, Róbert and Fustero, Santos and Lackfi, Ágnes and Hornyánszky, Gábor and Kiss, Loránd (2025) Studies on the Synthesis of Some Functionalized Azaheterocycles through Oxidative Ring Opening/Ring Closing by Reductive Amination. ASIAN JOURNAL OF ORGANIC CHEMISTRY, 14 (4). ISSN 2193-5807

[img]
Preview
Text
AsianJOrgChem-2025-Nonn-StudiesontheSynthesisofSomeFunctionalizedAzaheterocyclesthroughOxidativeRing.pdf
Available under License Creative Commons Attribution.

Download (4MB) | Preview

Abstract

Selected functionalized saturated azaheterocycles have been prepared by ring expansion from their unsaturated counterpart or using substituted cycloalkenes involving oxidative ring opening/ring closing by reductive amination. Studies have been conducted regarding the outcome of the transformations, the effect of the ring strain, and stereocontrol. The synthesized amino acid derivatives possessing either an aryl or fluorine element in their structure might be relevant building blocks for foldamer chemistry.

Item Type: Article
Additional Information: The authors gratefully acknowledge financial support from the National Research, Development and Innovation Office of Hungary (NKFIH/OTKA FK 145394 and K 142266). Project no. RRF-2.3.1-21-2022-00015 has been implemented with the support provided by the European Union. This work was supported by the János Bolyai Research Scholarship to M. N. of the Hungarian Academy of Sciences.
Subjects: Q Science / természettudomány > QD Chemistry / kémia
SWORD Depositor: MTMT SWORD
Depositing User: MTMT SWORD
Date Deposited: 12 Sep 2025 11:12
Last Modified: 12 Sep 2025 11:12
URI: https://real.mtak.hu/id/eprint/224081

Actions (login required)

Edit Item Edit Item