Genetic variation within and relationships among five subpopulations of Slovak Thoroughbred

Šátková-Jakabová, Daniela and Trandžík, J. and Hudecová-Kvasňáková, Ľudmila and Hegedüšová-Zetochová, Erika and Bugarský, A. and Buleca Jr., J. and Zöldág, L. and Jakab, F. and Fľak, P. (2004) Genetic variation within and relationships among five subpopulations of Slovak Thoroughbred. Acta Veterinaria Hungarica, 52 (3). pp. 259-265. ISSN 0236-6290

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Abstract

Genetic variation at six microsatellite loci was analysed for five Thoroughbred subpopulations to determine the magnitude of genetic differentiation and the genetic relationships among the subpopulations. Significant deviations from Hardy-Weinberg equilibrium were shown for a number of locus-population combinations, with all subpopulations. The genetic diversities and relationships of five Thoroughbred subpopulations were evaluated using six microsatellites recommended by the International Society of Animal Genetics (ISAG). The allele frequencies, the effective numbers of alleles, and the observed and expected heterozygosities were calculated. POPGENE v. 1.31 (Yeh et al., 1997) was used to test for deviations from the Hardy-Weinberg (H-W) equilibrium and to assign F_IS estimates (Weir, 1990). The utility of microsatellites for evaluating genetic diversity of horses is discussed.

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