Items where Author is "Penke, Botond"

Article

Penke, Botond and Szűcs, Mária and Bogár, Ferenc (2023) Alzheimer-kór: le tudjuk-e lassítani a betegséget, lesz-e oki terápia? BIOKÉMIA: A MAGYAR BIOKÉMIAI EGYESÜLET FOLYÓIRATA, 48 (2). pp. 10-29. ISSN 0133-8455

Penke, Botond and Szűcs, Mária and Bogár, Ferenc (2023) New Pathways Identify Novel Drug Targets for the Prevention and Treatment of Alzheimer’s Disease. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (6). ISSN 1661-6596

Váczi, Sándor and Barna, Lilla and Laczi, Krisztián and Tömösi, Ferenc and Rákhely, Gábor and Penke, Botond and Fülöp, Lívia and Bogár, Ferenc and Janáky, Tamás and Deli, Mária A. and Mezei, Zsófia (2022) Effects of Sub-Chronic, in vivo Administration of Sigma Non-Opioid Intracellular Receptor 1 Ligands on Platelet and Aortic Arachidonate Cascade in Rats. EUROPEAN JOURNAL OF PHARMACOLOGY, 925. pp. 1-10. ISSN 0014-2999 (print); 1879-0712 (online)

Váczi, Sándor and Barna, Lilla and Laczi, Krisztián and Tömösi, Ferenc and Rákhely, Gábor and Penke, Botond and Fülöp, Lívia and Bogár, Ferenc and Janáky, Tamás and Deli, Mária A. and Mezei, Zsófia (2022) Effects of Sub-Chronic, in vivo Administration of Sigma-1 Receptor Ligands on Platelet and Aortic Arachidonate Cascade in Streptozotocin-Induced Diabetic Rats. PLOS ONE, 17 (11). pp. 1-23. ISSN 1932-6203

Szögi, Titanilla and Borbély, Emőke and Schuster, Ildikó and Bozsó, Zsolt and Sántha, Miklós and Tóth, Melinda E. and Penke, Botond and Fülöp, Lívia (2022) Examination of Longitudinal Alterations in Alzheimer’s Disease-Related Neurogenesis in an APP/PS1 Transgenic Mouse Model, and the Effects of P33, a Putative Neuroprotective Agent Thereon. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (18). pp. 1-17. ISSN 1422-0067

Dukay, Brigitta and Walter, Fruzsina R. and Vigh, Judit P. and Barabási, Beáta and Hajdu, Petra and Balassa, Tamás and Migh, Ede and Kincses, András and Hoyk, Zsófia and Szögi, Titanilla and Borbély, Emőke and Csoboz, Bálint and Horváth, Péter and Fülöp, Lívia and Penke, Botond and Vigh, László and Deli, Mária A. and Sántha, Miklós and Tóth, Melinda E. (2021) Neuroinflammatory processes are augmented in mice overexpressing human heat-shock protein B1 following ethanol-induced brain injury. JOURNAL OF NEUROINFLAMMATION, 18. pp. 1-24. ISSN 1742-2094

Dvorácskó, Szabolcs and Lázár, László and Fülöp, Ferenc and Palkó, Márta and Zalán, Zita and Penke, Botond and Fülöp, Lívia and Tömböly, Csaba and Bogár, Ferenc (2021) Novel High Affinity Sigma-1 Receptor Ligands from Minimal Ensemble Docking-Based Virtual Screening. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22 (15). pp. 1-17. ISSN 1661-6596 (print); 1422-0067 (online)

Szogi, Titanilla and Schuster, Ildiko and Borbely, Emoke and Gyebrovszki, Andrea and Bozso, Zsolt and Gera, János and Rajkó, Róbert and Sántha, Miklós and Penke, Botond and Fülöp, Lívia (2019) Effects of the Pentapeptide P33 on Memory and Synaptic Plasticity in APP/PS1 Transgenic Mice: A Novel Mechanism Presenting the Protein Fe65 as a Target. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20 (12). No. 3050. ISSN 1661-6596

Hoyk, Zsófia and Tóth, Erzsébet Melinda and Lénárt, Nikolett and Nagy, Dóra and Dukay, Brigitta and Csefová, Alexandra and Zvara, Ágnes and Seprényi, György and Kincses, András and Walter, Fruzsina and Veszelka, Szilvia and Vigh, Judit and Barabási, Beáta and Harazin, András and Kittel, Ágnes and Puskás, László and Penke, Botond and Vigh, László and Deli, Mária Anna and Sántha, Miklós (2018) Cerebrovascular Pathology in Hypertriglyceridemic APOB-100 Transgenic Mice. FRONTIERS IN CELLULAR NEUROSCIENCE, 12. No.-380. ISSN 1662-5102

Penke, Botond and Paragi, Gábor and Gera, János and Berkecz, Róbert and Kovács, Zsolt and Crul, Tim and Vigh, László (2018) The Role of Lipids and Membranes in the Pathogenesis of Alzheimer's Disease. CURRENT ALZHEIMER RESEARCH, 15 (13). pp. 1191-1212. ISSN 1567-2050

Kasza, Ágnes and Hunya, Ákos and Frank, Z. and Fülöp, Ferenc and Török, Zsolt and Balogh, Gábor and Sántha, Miklós and Bálind, Árpád and Horváth, Ibolya and Vigh, László and Penke, Botond (2016) Dihydropyridine Derivatives Modulate Heat Shock Responses and have a Neuroprotective Effect in a Transgenic Mouse Model of Alzheimer's Disease. JOURNAL OF ALZHEIMERS DISEASE, 53 (2). pp. 557-571. ISSN 1387-2877

Bogár, Ferenc and Simon, Dóra and Bozsó, Zsolt and Janáky, Tamás and Veszelka, Szilvia and Tóth E., Andrea and Deli A., Mária and Borics, Attila and Násztor, Zoltán and Gyebrovszki, Andrea and Penke, Botond and Fülöp, Lívia (2015) Opposite effect of Ca2+/Mg2+ ions on the aggregation of native and precursor-derived Aβ42. STRUCTURAL CHEMISTRY, 26 (5). pp. 1389-1403. ISSN 1040-0400

Varga, Edina and Juhász, Gábor and Bozsó, Zsolt and Penke, Botond and Fülöp, Lívia and Szegedi, Viktor (2015) Amyloid-β1-42 Disrupts Synaptic Plasticity by Altering Glutamate Recycling at the Synapse. Journal of Alzheimer's disease : JAD, 45 (2). pp. 449-56. ISSN 1875-8908

Murvai, Csilla Ünige and Somkuti, Judit and Smeller, László and Penke, Botond and Kellermayer, Miklós (2015) Structural and nanomechanical comparison of epitaxially and solution-grown amyloid β25-35 fibrils. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 1854 (5). pp. 327-332. ISSN 1570-9639

Penke, Botond and Fülöp, Lívia (2015) Életmód- és táplálkozási-faktorok szerepe az Alzheimer-kór prevenciójában. BIOKÉMIA: A MAGYAR BIOKÉMIAI EGYESÜLET FOLYÓIRATA, 39 (4). pp. 39-52. ISSN 0133-8455

Varga, Edina and Juhász, Gábor and Bozsó, Zsolt and Penke, Botond and Fülöp, Lívia and Szegedi, Viktor (2014) Abeta(1-42) Enhances Neuronal Excitability in the CA1 via NR2B Subunit-Containing NMDA Receptors. Neural Plasticity. No.-584314. ISSN 2090-5904, ESSN: 1687-5443

Koivisto, Hennariikka and Grimm, Marcus O. and Rothhaar, Tatjana L. and Berkecz, Róbert and Lütjohann, Dieter and Giniatullina, Rajsa and Takalo, Mari and Miettinen, Pasi O. and Lahtinen, Hanna-Maija and Giniatullin, Rashid and Penke, Botond and Janáky, Tamás and Broersen, Laus M. and Hartmann, Tobias and Tanila, Heikki (2014) Special lipid-based diets alleviate cognitive deficits in the APPswe/PS1dE9 transgenic mouse model of Alzheimer's disease independent of brain amyloid deposition. Journal of Nutritional Biochemistry, 25 (2). 157 - 169. ISSN 0955-2863, ESSN: 1873-4847

Veszelka, Szilvia and Tóth, Andrea E. and Walter, Fruzsina R. and Datki, Zsolt and Mózes, Emese and Fülöp, Lívia and Bozsó, Zsolt and Hellinger, Éva and Vastag, Mónika and Orsolits, Barbara and Környei, Zsuzsanna and Penke, Botond and Deli, Mária Anna (2013) Docosahexaenoic acid reduces amyloid β-induced toxicity in cells of the neurovascular unit. JOURNAL OF ALZHEIMERS DISEASE, 36 (3). pp. 487-501. ISSN 1387-2877

Kellermayer, Miklós and Murvai, Csilla Ünige and Horváth, Andrea and Laszloffi, E. and Soos, K. and Penke, Botond (2013) Epitaxial assembly dynamics of mutant amyloid beta25-35_N27C fibrils explored with time-resolved scanning force microscopy. BIOPHYSICAL CHEMISTRY, 184. pp. 54-61. ISSN 0301-4622

Tóth, Erzsébet Melinda and Szegedi, Viktor and Varga, Edina and Juhász, Gábor and Horváth, János and Csibrány, Balázs and Alföldi, Róbert and Lénárt, Nikolett and Penke, Botond and Sántha, Miklós (2013) Overexpression of Hsp27 ameliorates symptoms of Alzheimer's disease in APP/PS1 mice. CELL STRESS & CHAPERONES, 18 (6). pp. 759-771. ISSN 1355-8145

Garro, Adriana D. and Olivella, Mónica S. and Bombasaro, José A. and Lima, Beatriz and Tapia, Alejandro and Feresin, Gabriela and Perczel, András and Somlai, Csaba and Penke, Botond and Cascales, Javier López and Rodríguez, Ana M. and Enriz, Ricardo D. (2013) Penetratin and Derivatives Acting as Antibacterial Agents. Chemical Biology & Drug Design , 82 (2). pp. 167-177. ISSN 1747-0285

Kékesi, Adrienna Katalin and Juhász, Gábor and Simor, Attila and Gulyássy, Péter and Szegő Éva, Mónika and Hunyadi-Gulyás, Éva and Darula, Zsuzsanna and Medzihradszky F., Katalin and Palkovics, Miklós and Penke, Botond and Czurkó, András (2012) Altered Functional Protein Networks in the Prefrontal Cortex and Amygdala of Victims of Suicide. PLOS ONE, 7. e50532. ISSN 1932-6203

Lénárt, Nikolett and Szegedi, Viktor and Juhász, Gábor and Kasztner, Anikó and Horváth, János and Bereczki, Erika and Tóth, Erzsébet Melinda and Penke, Botond and Sántha, Miklós (2012) Increased Tau Phosphorylation and Impaired Presynaptic Function in Hypertriglyceridemic ApoB-100 Transgenic Mice. PLOS ONE, 7 (9). ISSN 1932-6203

Hetényi, Anasztázia and Fülöp, Lívia and Martinek, Tamás and Wéber, Edit and Soós, Katalin and Penke, Botond (2008) Ligand-Induced Flocculation of Neurotoxic Fibrillar Abeta(1-42) by Noncovalent Crosslinking. CHEMBIOCHEM, 9 (5). pp. 748-757. ISSN 1439-4227

Szegedi, Viktor and Juhász, Gábor and Rózsa, Éva and Juhász-Vedres, Gabriella and Datki, Zsolt and Fülöp, Lívia and Bozsó, Zsolt and Lakatos, Andrea and Laczkó, Ilona and Farkas, Tamás and Kis, Zsolt and Tóth, Géza and Soós, Katalin and Zarándi, Márta and Budai, Dénes and Toldi, József and Penke, Botond (2006) Endomorphin-2, an endogenous tetrapeptide, protects against A beta 1-42 in vitro and in vivo. FASEB Journal, 20 (8). pp. 1191-1193. ISSN 0892-6638 (print), 1530-6860 (online)

Shemer, Isaac and Holmgren, Carl and Min, Rogier and Fülöp, Lívia and Zilberter, Misha and Sousa, Kyle M. and Farkas, Tamás and Härtig, Wolfgang and Penke, Botond and Burnashev, Nail and Tanila, Heikki and Zilberter, Yuri and Harkany, Tibor (2006) Non-fibrillar beta-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors. European Journal of Neuroscience, 23 (8). pp. 2035-2047. ISSN 0953-816X (print), 1460-9568 (online)

Szegedi, Viktor and Fülöp, Lívia and Farkas, Tamás and Rózsa, E. and Robotka, H. and Kis, Zsolt and Penke, Z. and Horváth, Szatmár and Molnár, Z. and Datki, Zsolt and Soós, Katalin and Toldi, József and Budai, D. and Zarándi, Márta and Penke, Botond (2005) Pentapeptides derived from A beta 1-42 protect modulatory effect of A beta fibrils - an in vivo electrophysiological study. Neurobiology of Disease, 18 (3). pp. 499-508. ISSN 0969-9961

Füvesi, Judit and Somlai, Csaba and Németh, Hajnalka and Varga, Hedvig and Kis, Zsolt and Farkas, Tamás and Károly, Norbert and Dobszay, Márton and Penke, Zsuzsa and Penke, Botond and Vécsei, László and Toldi, József (2004) Comparative study on the effects of kynurenic acid and glucosamine–kynurenic acid. Pharmacology Biochemistry and Behavior, 77 (1). pp. 95-102. ISSN 0091-3057

Fenyő, R. and Timár, Zoltán and Pálinkó, István and Penke, Botond (2000) The triplex forming ability of nonnatural nucleobases: a computational approach. JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, 496. pp. 101-105. ISSN 0166-1280

Fenyo, R. and Timár, Zoltán and Pálinkó, István and Penke, Botond (1999) Computer aided design of triplet forming artificial nucleobases. NUCLEOSIDES AND NUCLEOTIDES, 18 (4-5). pp. 1127-1129. ISSN 0732-8311

Obál, F. and Kovalzon, V.M. and Kalikhevich, V.N. and Török, A. and Alföldi, P. and Sáry, Gyula and Hajós, M. and Penke, Botond (1986) Structure-activity relationship in the effects of delta-sleep-inducing peptide (DSIP) on rat sleep. Pharmacology Biochemistry and Behavior, 24 (4). pp. 889-894. ISSN 0091-3057

Obál, F. and Török, A. and Alföldi, P. and Sáry, Gyula and Hajós, M. and Penke, Botond (1985) Effects of intracerebroventricular injection of Delta Sleep-Inducing Peptide (DSIP) and an analogue on sleep and brain temperature in rats at night. Pharmacology Biochemistry and Behavior, 23 (6). pp. 953-957. ISSN 0091-3057

Varga, László and Fodor, Eleonóra and Holzinger, Gábor and Németh, József and Baláspiri, Lajos and Penke, Botond and Kovács, Lívia and Szabó, Imre and Ormai, Sándor and Varró, Vince (1982) A pentagasztrin katabolizmus in vitro és in vivo vizsgálata patkányban. A MAGYAR TUDOMÁNYOS AKADÉMIA V. ORVOSI TUDOMÁNYOK OSZTÁLYÁNAK KÖZLEMÉNYEI, 33 (1). pp. 25-40. ISSN 0030-6045

Varga, László and Kovács, Istvánné and Penke, Botond and Baláspiri, Lajos and Pallai, Péter and Varró, Vince (1978) Újabb adatok a BOC-glycin pentapeptidamid (pentagastrin) in vivo metabolizmusához. A MAGYAR TUDOMÁNYOS AKADÉMIA V. ORVOSI TUDOMÁNYOK OSZTÁLYÁNAK KÖZLEMÉNYEI, 29 (2). pp. 107-122.

Varga, László and Náfrádi, József and Csernay, László and Baláspiri, Lajos and Penke, Botond and Varró, Vince (1973) A gastrin biológiailag aktív végcsoportjának a glycin-pentagastrinnak metabolizmusáról. A Magyar Tudományos Akadémia V. Orvosi Tudományok Osztályának Közleményei, 24 (1). pp. 13-32. ISSN 0030-6045

Monograph

Penke, Botond and Bánfi, Annamária and Bodóné Sipos, Eszter and Bogár, Ferenc and Borbély, Emőke and Bozsó, Zsolt and Datki, Zsolt László and Dékány, Imre and Földi, István and Fülöp, Lívia and Hornok, Viktória and Hunya, Ákos Gábor and Janáky, Tamás and Juhász, Gábor and Kasza, Ágnes and Kele, Zoltán and Kovács, Lajos and Kőrösi, László Tamás and Kőrösiné Papp, Szilvia and Kun, Róbert and Kupihár, Zoltán and Majzik, Andrea and Paragi, Gábor and Patakfalvi, Rita and Simon, Dóra and Szabó, Tamás and Szabó, Zoltán and Szegedi, Viktor and Tóth, Gábor and Váradi, Györgyi (2012) Béta-amiloid peptidek aggregációja és kölcsönhatása fehérjékkel; új neuroprotektív vegyületek alkalmazása az Alzheimer-kór megelőzésére = Beta-amyloid aggregation and interaction with proteins; novel neuroprotective compounds for prevention of Alzheimer's disease. Project Report. OTKA.

Körtvélyesi, Tamás and Bogár, Ferenc and Kovács, Lajos and Pálinkó, István and Paragi, Gábor and Penke, Botond (2009) Peptid nukleinsavak szerkezete - elméleti számítások = Peptide Nucleic Acids - Theoretical Approach. Project Report. OTKA.

Penke, Botond and Bogár, Ferenc and Hornyák, Miklós Gábor and Janáky, Tamás and Kele, Zoltán and Monostori, Éva and Paragi, Gábor and Somlai, Csaba and Szűcs, Mária and Tóth, Gézáné and Tóth, Géza and Tóth, Gábor and Váradi, Györgyi and Zarándi, Márta (2009) Peptidek és fehérjék, és peptid-nukleinsavak szintézise, szerkezetvizsgálata és biológiai szerepe = Synthesis, structure investigation and biological role of peptides, proteins and peptide nucleic acids. Project Report. OTKA.

Csizmadia, G. Imre and Penke, Botond and Viskolcz, Béla (2007) A gyökfogó dokozahexaénsav mint agyvédő = Docosahexaenoic acid (DHA) as a free radical scavenger brain protector. Project Report. OTKA.

Vígh, László and Balogh, Gábor and Balogi, Zsolt and Bereczki, Erika and Boros, Imre Miklós and Csabai, Péter and Debreceny, Mónika and Glatz, Attila and Gwendolyn C., Barcelo and Gyorfy, Zsuzsanna and Hogyes, Endre and Horváth, Ibolya and Joó, Ferenc and Kitajka, Klára and Klement, Éva and Medzihradszky, Katalin and Nagy, Eniko and Natalia, Shigapova and Novákné Papp, Éva and Papp, Gábor and Penke, Botond and Puskás, László and Sántha, Miklós and Török, Zsolt and Zvara, Ágnes (2007) Lipid-membrán iskola a Szegedi Biológiai Központban = Lipid-membrane school at the Biological Research Center. Project Report. OTKA.