Sápi, Johanna and Drexler, Dániel András and Kovács, Levente (2016) Comparison of protocol based cancer therapies and discrete controller based treatments in the case of endostatin administration. In: 2016 IEEE International Conference on Systems, Man, and Cybernetics Conference Proceedings. IEEE, Budapest, pp. 3830-3835. ISBN 978-1-5090-1819-2
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Abstract
In the medical practice, there are several methods to administer anti-cancer drugs. A commonly used method is the intermittent bolus doses (BD) administration when the patient receives drug on given days and the therapy has rest periods between the injections. The amount of bolus doses can be the maximum tolerated dose (MTD) or less. Anti-cancer drug can be administered in low doses over prolonged periods without extended rest periods which is called as low-dose metronomic therapy (LDM). In addition, continuous infusion therapy is applicable within clinical environment, not yet as a portable device. The major disadvantage of these methods is the empiricism associated with determining the optimal biologic dose (OBD). In order to solve the problem, we have designed discrete-time controllers which realize automated optimal treatments.
Item Type: | Book Section |
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Additional Information: | Workshop paper: “Women in Engineering” |
Subjects: | Q Science / természettudomány > QA Mathematics / matematika > QA75 Electronic computers. Computer science / számítástechnika, számítógéptudomány R Medicine / orvostudomány > RC Internal medicine / belgyógyászat > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry / idegkórtan, neurológia, pszichiátria T Technology / alkalmazott, műszaki tudományok > TA Engineering (General). Civil engineering (General) / általános mérnöki tudományok |
SWORD Depositor: | MTMT SWORD |
Depositing User: | MTMT SWORD |
Date Deposited: | 16 Jan 2017 08:50 |
Last Modified: | 16 Jan 2017 08:50 |
URI: | http://real.mtak.hu/id/eprint/45559 |
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