Items where Author is "Dobó, József"

Article

Dürvanger, Zsolt and Boros, Eszter and Nagy, Zoltán Attila and Hegedüs, Rózsa and Megyeri, Márton and Dobó, József and Gál, Péter and Schlosser, Gitta (Vácziné) and Ángyán, Annamária F. and Gáspári, Zoltán and Perczel, András and Harmat, Veronika and Mező, Gábor and K. Menyhárd, Dóra and Pál, Gábor (2022) Directed Evolution-Driven Increase of Structural Plasticity Is a Prerequisite for Binding the Complement Lectin Pathway Blocking MASP-Inhibitor Peptides. ACS CHEMICAL BIOLOGY, 17. 969 -986. ISSN 1554-8929

Nagy, Attila Zoltán and Héja, Dávid and Bencze, Dániel and Kiss, Bence and Boross, Eszter and Szakács, Dávid and Fodor, Krisztián and Wilmanns, Matthias and Kocsis, Andrea and Dobó, József and Gál, Péter and Harmat, Veronika and Pál, Gábor (2022) Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation. JOURNAL OF BIOLOGICAL CHEMISTRY, 298. p. 101985. ISSN 0021-9258

Debreczeni, Márta Lídia and Székács, Inna and Kovács, Boglárka and Saftics, András and Kurunczi, Sándor and Gál, Péter and Dobó, József and Cervenák, László and Horváth, Róbert (2020) Human primary endothelial label-free biochip assay reveals unpredicted functions of plasma serine proteases. SCIENTIFIC REPORTS, 10. pp. 1-14. ISSN 2045-2322

Holers, V. Michael and Borodovsky, Anna and Scheinman, Robert I. and Ho, Nhu and Ramos Ramirez, Joseline and Dobó, József and Gál, Péter (2020) Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D. FRONTIERS IN IMMUNOLOGY, 11. pp. 1-18. ISSN 1664-3224

Nagy, Zoltán Attila and Szakács, Dávid and Boros, Eszter and Héja, Dávid and Vígh, Eszter and Sándor, Noémi and Józsi, Mihály and Oroszlán, Gábor and Dobó, József and Gál, Péter and Pál, Gábor (2019) Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum. PLOS PATHOGENS, 15 (12). pp. 1-33. ISSN 1553-7366 (print); 1553-7374 (online)

Nagy-Debreczeni, Márta Lídia and Németh, Zsuzsanna and Kajdácsi, Erika and Schwaner, Endre and Makó, Veronika and Masszi, András and Doleschall, Zoltán and Rigó, János and Walter, Fruzsina and Deli, Mária Anna and Pál, Gábor and Dobó, József and Gál, Péter and Cervenak, László (2019) MASP-1 Increases Endothelial Permeability. FRONTIERS IN IMMUNOLOGY, 10. No.-991. ISSN 1664-3224

Jenny, Lorenz and Noser, Danilo and Larsen, Julie Brogaard and Dobó, József and Gál, Péter and Pál, Gábor (2019) MASP-1 of the complement system alters fibrinolytic behaviour of blood clots. MOLECULAR IMMUNOLOGY, 114. pp. 1-9. ISSN 0161-5890

Dobó, József and Kocsis, Andrea and Gál, Péter (2018) Be on Target: Strategies of Targeting Alternative and Lectin Pathway Components in Complement-Mediated Diseases. FRONTIERS IN IMMUNOLOGY, 9. pp. 1-22. ISSN 1664-3224

Paréj, Katalin and Kocsis, Andrea and Enyingi, Csenge and Dani, Ráhel and Oroszlán, Gábor and Beinrohr, László and Dobó, József and Závodszky, Péter and Pál, Gábor and Gál, Péter (2018) Cutting Edge: A New Player in the Alternative Complement Pathway, MASP-1 Is Essential for LPS-Induced, but Not for Zymosan-Induced, Alternative Pathway Activation. JOURNAL OF IMMUNOLOGY, 200 (7). pp. 2247-2252. ISSN 0022-1767

Jenny, Lorenz and Dobó, József and Gál, Péter and Pál, Gábor and Lam, Wilbur A. and Schroeder, Verena (2018) MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model. PLOS ONE, 13 (1). pp. 1-14. ISSN 1932-6203

Oroszlán, Gábor and Dani, Ráhel and Szilágyi, András and Závodszky, Péter and Thiel, Steffen and Gál, Péter and Dobó, József (2017) Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism. FRONTIERS IN IMMUNOLOGY, 8. pp. 1-14. ISSN 1664-3224

Jani, Péter K. and Schwaner, Endre and Kajdácsi, Erika and Debreczeni, Márta L. and Salánki, Rita Zsanett and Dobó, József and Doleschallf, Zoltán and Rigó, János and Szabó, Bálint and Gál, Péter and Cervenak, László (2016) Complement MASP-1 enhances adhesion between endothelial cellsand neutrophils by up-regulating E-selectin expression. Molecular Immunology, 75. pp. 38-47. ISSN 0161-5890

Oroszlán, Gábor and Kortvely, Előd and Szakács, Dávid and Kocsis, Andera and Dammeier, Sascha and Závodszky, Péter and Pál, Gábor and Gál, Péter and Dobó, József (2016) MASP-1 and MASP-2 Do Not Activate Pro-Factor D in Resting Human Blood, whereas MASP-3 Is a Potential Activator: Kinetic Analysis Involving Specific MASP-1 and MASP-2 Inhibitors. Journal of Immunology, 196. pp. 857-865. ISSN 0022-1767, ESSN: 1550-6606

Dobó, József and Szakács, Dávid and Oroszlán, Gábor and Kortvely, Elod and Kiss, Bence and Boros, Eszter and Szász, Róbert and Závodszky, Péter and Gál, Péter and Pál, Gábor (2016) MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked. SCIENTIFIC REPORTS, 2016 (6). No. 31877. ISSN 2045-2322

Kjaer, Troels R. and Jensen, L. and Hansen, A. and Dani, R. and Jensenius, J. C. and Dobó, József and Gál, Péter (2016) Oligomerization of Mannan-binding Lectin Dictates Binding Properties and Complement Activation. Scandinavian Journal of Immunology, 84 (1). pp. 12-19. ISSN 0300-9475, ESSN: 1365-3083

Sajó, Ráchel and Tőke, Orsolya and Hajdú, István and Jankovics, Hajnalka and Micsonai, András and Dobó, József and Kardos, József (2016) Structural plasticity of the Salmonella FliS flagellar export chaperone. FEBS LETTERS, 590 (8). pp. 1103-1113. ISSN 0014-5793

Dobó, József and Pál, Gábor and Cervenak, László and Gál, Péter (2016) The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond. IMMUNOLOGICAL REVIEWS, 274. pp. 98-111. ISSN 0105-2896

Jenny, Lorenz and Dobó, József and Gál, Péter and Schroeder, Verena (2015) MASP-1 of the complement system promotes clotting via prothrombin activation. MOLECULAR IMMUNOLOGY, 65 (2). pp. 398-405. ISSN 0161-5890

Paréj, Katalin and Hermann, Ágnes and Donáth, Nóra and Závodszky, Péter and Gál, Péter and Dobó, József (2014) Dissociation and re-association studies on the interaction domains of mannan-binding lectin (MBL)-associated serine proteases, MASP-1 and MASP-2, provide evidence for heterodimer formation. MOLECULAR IMMUNOLOGY, 59 (1). pp. 1-9. ISSN 0161-5890

Jani, P. K. and Kajdacsi, E. and Megyeri, M. and Dobó, József and Doleschall, Z. and Futosi, K. and Timar, Cs. I. and Mocsai, A. and Mako, V. and Gal, P. and Cervenak, L. (2014) MASP-1 Induces a Unique Cytokine Pattern in Endothelial Cells: A Novel Link between Complement System and Neutrophil Granulocytes. PLOS ONE, 9 (1). e87104. ISSN 1932-6203

Dobó, József and Schroeder, Verena and Jenny, Lorenz and Cervenak, László and Závodszky, Péter and Gál, Péter (2014) Multiple roles of complement MASP-1 at the interface of innate immune response and coagulation. MOLECULAR IMMUNOLOGY, 61 (2). pp. 69-78. ISSN 0161-5890

Megyeri, Márton and Jani, Péter K: and Kajdácsi, Erika and Dobó, József and Schwaner, Endre and Major, Balázs and Rigó, János and Závodszky, Péter and Cervenak, László and Gál, Péter (2014) Serum MASP-1 in complex with MBL activates endothelial cells. MOLECULAR IMMUNOLOGY, 59 (1). pp. 39-45. ISSN 0161-5890

Sajó, Ráchel and Liliom, Károly and Muskotal, A. and Klein, A. and Závodszky, Péter and Vonderviszt, Ferenc and Dobó, József (2014) Soluble components of the flagellar export apparatus, FliI, FliJ, and FliH, do not deliver flagellin, the major filament protein, from the cytosol to the export gate. BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR CELL RESEARCH, 1843 (11). pp. 2414-2423. ISSN 0167-4889

Megyeri, Márton and Harmat, Veronika and Major, Balázs and Végh, Ádám and Balczer, Júlia and Héja, Dávid and Szilágyi, Katalin and Datz, Dániel and Pál, Gábor and Závodszky, Péter and Gál, Péter and Dobó, József (2013) Quantitative Characterization of the Activation Steps of Mannan-binding Lectin (MBL)-associated Serine Proteases (MASPs) Points to the Central Role of MASP-1 in the Initiation of the Complement Lectin Pathway. Journal of Biological Chemistry, 288 (13). pp. 8922-8934. ISSN 0021-9258 (print) 1083-351X (online)

Paréj, Katalin and Dobó, József and Závodszky, Péter and Gál, Péter (2013) The control of the complement lectin pathway activation revisited: both C1-inhibitor and antithrombin are likely physiological inhibitors, while α2-macroglobulin is not. Molecular immunology, 54. pp. 415-422. ISSN 1872-9142

Book Section

Varga, Lilian and Dobó, József (2014) C1 inhibitor: quantification and purification. In: The Complement System. Humana Press, New York, pp. 189-205.

Monograph

Závodszky, Péter and Barna, László and Beinrohr, László and Cseh, Sándor and Cseh-Szilágyi, Katalin and Dobó, József and Gál, Péter and Gráczer, Éva and Gyimesi, Gergely and Györffy, Dániel and Hajdú, István and Kamondi, Szilárd and Kazinczyné Dr. Vas, Mária and Kocsis, Andrea and Lorincz, Zsolt and Major, Balázs and Matkovicsné Dr. Varga, Andrea and Megyeri, Márton and Perbiróné Szabó, Judit and Pollnerné Flachner, Beáta and Sajó, Ráchel and Szaszkó, Mária and Szilágyi, András and Varga, János and Végh, Barbara Márta and Vonderviszt, Ferenc (2013) Fehérjék konformációs dinamikája mint a biomolekuláris felismerés és jelátvitel meghatározó eleme = Protein conformational dynamics as a key determinant in biomolecular recognition and signal transmission. Project Report. OTKA.

Závodszky, Péter and Barna, László and Beinrohr, László and Borbola, Ildikó and Cseh-Szilágyi, Katalin and Dobó, József and Gál, Péter and Gyimesi, Gergely and Hajdú, István and Juhász, Tünde and Kamondi, Szilárd and Kazinczyné Vas, Mária and Kocsis, Andrea and Major, Balázs and Pollnerné Flachner, Beáta and Sebestyén, Edina and Szavicskó, István and Végh, Barbara Márta and Vonderviszt, Ferenc (2009) Enzimreakciók vizsgálata a moduláris szerveződés, az atomi kölcsönhatás és a kvantummechanika szintjein. A fehérje biofizika tudományos iskolája = Insight into the Enzyme Action at Levels of modular Organization, Atomic Interactions and Quantum-Mechanics. School of Protein Biophysics. Project Report. OTKA.

Conference or Workshop Item

Schwaner, Endre and Jani, Péter K. and Kajdácsi, Erika and Debreczeni, Márta L. and Dobó, József and Gál, Péter and Ungai-Salánki, Rita and Szabó, Bálint and Cervenak, László (2015) ASSESSMENT OF CELL ADHESION BETWEEN COMPLEMENT MASP-1 INDUCED ENDOTHELIAL CELLS AND NEUTROPHILS. In: Magyar Immunológiai Társaság 44. Vándorgyűlésére. (Submitted)