DASH dietary patterns associated with allostatic load in American adults on the basis of NHANES database (2017–2020)

Li, W.J. and Li, Y.H. (2025) DASH dietary patterns associated with allostatic load in American adults on the basis of NHANES database (2017–2020). ACTA ALIMENTARIA: AN INTERNATIONAL JOURNAL OF FOOD SCIENCE, 54 (2). pp. 216-225. ISSN 0139-3006

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Abstract

Allostatic load (AL) is a comprehensive physiologic measure of the body's chronic stress response and is associated with physical and mental health risks. The function of DASH diet (Dietary Approaches to Stop Hypertension) model in the development of AL is unclear. The relationship between the DASH score and AL was examined in this study. 1,565 US adults from NHANES database 2017–2020 were selected for the study, and DASH dietary pattern was assessed using DASH score, and ≥4.5 indicated compliance with DASH diet. AL was calculated using 11 biomarkers, and a score >3 indicated high levels. The relationship between DASH score and AL was analysed using logistic regression. In this study, a high AL prevalence of 35.4% ( n = 555) was found. In the unadjusted model, a high DASH score was associated with a low level of AL [OR = 0.458, 95% CI (0.306, 0.687), P < 0.001], and this relationship persisted in the adjusted model [OR = 0.473, 95% CI (0.310, 0.720), P < 0.001]. DASH score are negatively associated with AL, and low DASH score increase the risk of high AL, which can adversely affect physical and mental health.

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